Effects of capsaicin on esophageal peristalsis in humans using high resolution manometry
Augmentation of distension-induced secondary peristalsis can be modulated by activation of capsaicin-sensitive afferents similar to mechanosensitive afferents. Capsaicin-induced augmentation of primary peristalsis isolates to the cholinergic-mediated proximal smooth muscle segment, which warrants study in ineffective esophageal motility to determine therapeutic potential.
Authors
- Chih‐Hsun Yi (ORCID: https://orcid.org/0000-0003-4183-061X)
- Wei‐Yi Lei (ORCID: https://orcid.org/0000-0003-0396-8677)
- Chien‐Lin Chen (ORCID: https://orcid.org/0000-0002-9084-8210)
- Chandra Prakash Gyawali (ORCID: https://orcid.org/0000-0002-3388-0660)
- Tso‐Tsai Liu
- Ming‐Wun Wong (ORCID: https://orcid.org/0000-0003-0676-6800)
- Jui‐Sheng Hung (ORCID: https://orcid.org/0000-0002-7866-964X)
Institutions
- Tzu Chi University (TW)
- Washington University in St. Louis (US)
Publication Details
- Journal
- Neurogastroenterology & Motility
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1111/nmo.14942
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00