Periodontal Ligament Reactions to Orthodontic Force: A Transcriptomic Study on Maxillary and Mandibular Human Premolars
The early reaction of the PDL to OF corresponds with increased bone resorption and decreased bone formation. After 28 days, bone formation became more prominent. The maxillary and mandibular PDL present asynchronous responses during OTM. These findings enhance our comprehension of the mechanisms underlying the origin-specific responses of PDL to different lengths of OF, which is potentially relevant in the development of personalized therapeutic strategies.
Authors
- María Cadenas de Llano‐Pérula (ORCID: https://orcid.org/0000-0003-4710-255X)
- Wannes Van Holm (ORCID: https://orcid.org/0000-0002-4735-9104)
- Catia Attanasio (ORCID: https://orcid.org/0000-0001-8077-5719)
- Chen Zong (ORCID: https://orcid.org/0000-0002-8376-7930)
- Mihai Tarce (ORCID: https://orcid.org/0000-0001-6466-5261)
- Mariano Simón Pedano (ORCID: https://orcid.org/0000-0002-7686-4476)
- Maria Georgopoulou (ORCID: https://orcid.org/0000-0003-0218-7430)
- Zuodong Zhao (ORCID: https://orcid.org/0000-0002-4235-1859)
Institutions
- Vlaams Instituut voor Biotechnologie (BE)
- VIB-KU Leuven Center for Brain & Disease Research (BE)
- University of Hong Kong (HK)
- KU Leuven (BE)
Publication Details
- Journal
- Journal of Periodontal Research
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1111/jre.13352
- Citations
- 9
- Primary Topic
- dental development and anomalies
- Type
- article
- Field-Weighted Citation Impact
- 2.10
Funders
- KU Leuven