Frozen Section Analysis of Sentinel Nodes in Patients With Oral Squamous Cell Carcinoma

In this systematic review and meta-analysis, evaluated studies showed various techniques, in which pooled sensitivity reached 0.71, providing a benchmark for comparison to other 1-stop approaches. Due to the high false-negative rate of approximately one-third of patients, intraoperative FS must always be supplemented by serial sectioning. On-table diagnosis remains a key objective for sentinel node biopsy, and FS detection may be improved by standardizing protocols.

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Publication Details

Journal
JAMA Otolaryngology–Head & Neck Surgery
Published
2024-10-10
DOI
https://doi.org/10.1001/jamaoto.2024.3094
Citations
2
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
1.16
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article

Frozen Section Analysis of Sentinel Nodes in Patients With Oral Squamous Cell Carcinoma

Clare Schilling, Selvam Thavaraj, Mark McGurk, Axel Sahovaler et al.
2 citations
JAMA Otolaryngology–Head & Neck Surgery
Head and Neck Cancer Studies
1.16
article

Frozen Section Analysis of Sentinel Nodes in Patients With Oral Squamous Cell Carcinoma

Clare Schilling, Selvam Thavaraj, Mark McGurk, Axel Sahovaler, Panagiotis Vrakas, Munir Abukhder
article en
2 citations

Abstract

In this systematic review and meta-analysis, evaluated studies showed various techniques, in which pooled sensitivity reached 0.71, providing a benchmark for comparison to other 1-stop approaches. Due to the high false-negative rate of approximately one-third of patients, intraoperative FS must always be supplemented by serial sectioning. On-table diagnosis remains a key objective for sentinel node biopsy, and FS detection may be improved by standardizing protocols.

JAMA Otolaryngology–Head & Neck SurgeryVol. 150(11)
University College Hospital (GB), King's College London (GB), University College London (GB), IMU University (MY)
Openalex Percentile: Top 21%
Head and Neck Cancer Studies
1.16
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