A besyian regularisation neural network approach for hepatitis B virus spread prediction and immune system therapy model

The primary aim of the article is to analyze the response of the human immune system when it encounters the hepatitis B virus. This is done using a mathematical system of differential equations. The differential equation system has six components, likely representing various aspects of the immune response or virus dynamics. A Bayesian regularization neural network has been presented in the process of training. These networks are employed to find solutions for different categories or scenarios related to hepatitis B infection. The Adams method is used to generate reference data sets. The back-propagated artificial neural network, based on Bayesian regularization, is trained and validated using the generated data. The data is divided into three sets: 90% for training and 5% each for testing and validation. The correctness and effectiveness of the proposed neural network model have been assessed using various evaluation metrics. The metrics have been used in this study are Mean Square Error (MSE), histogram errors, and regression plots. These measures provide support to the neural network to approximate the immune response to the hepatitis B virus.

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Publication Details

Journal
Scientific Reports
Published
2024-10-10
DOI
https://doi.org/10.1038/s41598-024-75336-x
Citations
5
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
1.93

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article

A besyian regularisation neural network approach for hepatitis B virus spread prediction and immune system therapy model

Mohammad Mahtab Alam, Qusain Haider, Ahmed M. Galal, Mubashar Arshad et al.
5 citations
Scientific Reports
Hepatitis B Virus Studies
1.93
article

A besyian regularisation neural network approach for hepatitis B virus spread prediction and immune system therapy model

Mohammad Mahtab Alam, Qusain Haider, Ahmed M. Galal, Mubashar Arshad, Laila A. Al‐Essa, Ali Hassan, Haile Habenom
article en
5 citations

Abstract

The primary aim of the article is to analyze the response of the human immune system when it encounters the hepatitis B virus. This is done using a mathematical system of differential equations. The differential equation system has six components, likely representing various aspects of the immune response or virus dynamics. A Bayesian regularization neural network has been presented in the process of training. These networks are employed to find solutions for different categories or scenarios related to hepatitis B infection. The Adams method is used to generate reference data sets. The back-propagated artificial neural network, based on Bayesian regularization, is trained and validated using the generated data. The data is divided into three sets: 90% for training and 5% each for testing and validation. The correctness and effectiveness of the proposed neural network model have been assessed using various evaluation metrics. The metrics have been used in this study are Mean Square Error (MSE), histogram errors, and regression plots. These measures provide support to the neural network to approximate the immune response to the hepatitis B virus.

Scientific ReportsVol. 14(1)
Princess Nourah bint Abdulrahman University (SA), Prince Sattam Bin Abdulaziz University (SA), Mansoura University (EG), Southern University of Science and Technology (CN), Abbottabad University of Science and Technology (PK), King Khalid University (SA), University of Gujrat (PK)
King Khalid University
Good health and well-being
Openalex Percentile: Top 13%
Hepatitis B Virus Studies
1.93
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