The association between structural connectivity and anti‐seizure medication response in patients with temporal lobe epilepsy
This study investigates the relationship between brain connectivity changes and glymphatic system function with antiseizure medication response in patients with temporal lobe epilepsy and hippocampal sclerosis. The research reveals that these patients show altered brain connectivity and glymphatic function compared to healthy individuals. A key finding is the strong link between a specific connectivity measure (assortativity coefficient) and antiseizure medication response, providing valuable insights that could influence epilepsy treatment and future research directions.
Authors
- Kang Min Park (ORCID: https://orcid.org/0000-0002-4229-7741)
- Junghae Ko (ORCID: https://orcid.org/0000-0002-0029-6847)
- Dong Ah Lee (ORCID: https://orcid.org/0000-0001-8114-1371)
- Sung Tae Kim (ORCID: https://orcid.org/0000-0002-3737-3850)
- Ho‐Joon Lee (ORCID: https://orcid.org/0000-0003-0831-6184)
Institutions
- Inje University Haeundae Paik Hospital (KR)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1002/epi4.13076
- Citations
- 4
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Inje University