Ultrastructural evaluation of adverse effects on dentine formation from systemic fluoride application in an experimental mouse model
High doses of systemic fluoride can cause dentine dysplasia. Both three-dimensional and microstructural analyses showed the structural, chemical and mechanical changes in the dentine and the mineralized tissue components, along with external resorption and pulp inflammation.
Authors
- Manabu Mizuhira
- Nanako Kuriki (ORCID: https://orcid.org/0000-0002-2931-3583)
- Eric T. Everett (ORCID: https://orcid.org/0000-0001-7801-5278)
- Henry Fergus Duncan (ORCID: https://orcid.org/0000-0001-8690-2379)
- Motoki Okamoto (ORCID: https://orcid.org/0000-0002-3759-5031)
- Shohei Yamashita (ORCID: https://orcid.org/0000-0003-0145-6467)
- Ria Achong‐Bowe
- M. Suzuki (ORCID: https://orcid.org/0000-0002-1732-0663)
- Susanne Brueckner
- Melanie Mendonca
- Yehuda Benjamin
- Jeffrey Thompson
Institutions
- University of North Carolina at Chapel Hill (US)
- Nova Southeastern University (US)
- Trinity College Dublin (IE)
- Dublin Dental University Hospital (IE)
- The University of Osaka (JP)
Publication Details
- Journal
- International Endodontic Journal
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1111/iej.14150
- Citations
- 9
- Primary Topic
- Fluoride Effects and Removal
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- National Institute of Dental and Craniofacial Research