Systematic analysis based on bioinformatics and experimental validation identifies <i>Alox5</i> as a novel therapeutic target of quercetin for sepsis
<i>Alox5</i> may be involved in the occurrence and development of multi-organ functional disturbances in sepsis and is a reliable target of quercetin against sepsis.
Authors
- Chu-Yun Liu
- He‐fan He (ORCID: https://orcid.org/0000-0003-0787-3173)
- Wei-can Chen
- Yu-Shen Yang (ORCID: https://orcid.org/0000-0003-0310-3999)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-7508-4160)
- Meng-Qin Pei
- Jin-Wei Liang
Institutions
- Fujian Medical University (CN)
- Second Affiliated Hospital of Fujian Medical University (CN)
- Zhuzhou Central Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1080/07853890.2024.2411015
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.36
Funders
- Natural Science Foundation of Fujian Province