The impact of the RTS,S malaria vaccine on uncomplicated malaria: evidence from the phase IV study districts, Upper East Region, Ghana, 2020–2022
The RTS,S malaria vaccine significantly reduced the burden of uncomplicated malaria among children aged 12-59 months in the implementing area. The sequential marginal declines in malaria incidence averted over the study period might be due to waning of protective immunity and acquisition of natural immunity as children age. Strengthening uptake of the currently recommended vaccines and other malaria control interventions is required to improve public health impact.
Authors
- Michael Rockson Adjei (ORCID: https://orcid.org/0000-0002-8813-1800)
- Peter Ofori Tweneboah
- Josephat Ana-Imwine Nyuzaghl
- Rafiq Okine (ORCID: https://orcid.org/0000-0002-9837-9172)
- Emmanuel Kofi Dzotsi
- Emmanuel Akwoulo Agyigewe Teviu
- Sally-Ann Ohene (ORCID: https://orcid.org/0000-0002-7511-5270)
- Janet Vanessa Baafi
- Martin Peter Grobusch
- Nana Akua Afriyie
Institutions
- World Health Organization - Pakistan (PK)
- University of Cape Town (ZA)
- Centre de Recherche Médicales de Lambaréné (GA)
- World Health Organization (CH)
- Amsterdam University Medical Centers (NL)
- Ghana Health Service (GH)
- University of Tübingen (DE)
- University of Amsterdam (NL)
Publication Details
- Journal
- Malaria Journal
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12936-024-05123-6
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.54