An integrative analysis based on multiple cell death patterns identifies an immunosuppressive subtype and establishes a prognostic signature in lower-grade glioma
The new cell death-based subtype system indicates several features of LGG biology and reveals novel insights into the use of precision medicine for treating LGG. The CDPM score could be used to predict the immunotherapy response and prognosis of LGG patients; moreover, it could indicate a novel direction for improving LGG management.
Authors
- Hao Lian
- Lilun Jin
- Jiajia Wang (ORCID: https://orcid.org/0000-0002-4878-3513)
- Kui Chen (ORCID: https://orcid.org/0000-0002-7994-413X)
- Shan Yan (ORCID: https://orcid.org/0000-0003-0794-3143)
Institutions
- Shanghai Jiao Tong University (CN)
- XinHua Hospital (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1080/07853890.2024.2412831
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44
Funders
- National Natural Science Foundation of China