Caspofungin formulations for buccal and sublingual mucosae anti-fungal infections: physicochemical characterization, rheological analysis, release and <i>ex vivo</i> permeability profiles
The developed formulations offer distinct advantages for treating oral candidiasis, with chitosan formulation emerging as the most promising due to its superior retention, mucoadhesion force, and spreadability, making it a potential candidate for further clinical investigation.
Authors
- María J. Rodríguez-Lagunas (ORCID: https://orcid.org/0000-0001-7870-8250)
- Lyda Halbaut (ORCID: https://orcid.org/0000-0002-6080-5340)
- Mireia Mallandrich (ORCID: https://orcid.org/0000-0001-9316-8459)
- Noelia Pérez-González (ORCID: https://orcid.org/0000-0001-6251-1752)
- Beatriz Clares (ORCID: https://orcid.org/0000-0001-6126-7890)
- Núria Bozal-de Febrer (ORCID: https://orcid.org/0000-0001-5363-3125)
- Ana Cristina Calpena (ORCID: https://orcid.org/0000-0002-4989-4821)
- Eliana B. Souto (ORCID: https://orcid.org/0000-0002-9737-6017)
- José Antonio Morales-Molina (ORCID: https://orcid.org/0000-0003-2705-5389)
Institutions
- University College Dublin (IE)
- Universidad de Granada (ES)
- Institute of Agrifood Research and Technology (ES)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Complejo Hospitalario Torrecárdenas (ES)
- Institut de Nanociència i Nanotecnologia de la Universitat de Barcelona
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Pharmaceutical Development and Technology
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1080/10837450.2024.2415545
- Citations
- 1
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.42