Deciphering the role of SAMHD1 in endometrial cancer progression
The results from this study underscore the potential of targeting the SAMHD1-TRIM27-PTEN axis as a therapeutic strategy in EC. By providing new insights into the molecular mechanisms underlying EC progression, our research supports the development of novel therapeutic approaches that could contribute to improve treatment strategies for patients with EC.
Authors
- Qicheng Deng
- Songyuan Xu (ORCID: https://orcid.org/0000-0001-8551-6863)
- Yang Shao (ORCID: https://orcid.org/0000-0002-8491-3610)
- Ping Qiang (ORCID: https://orcid.org/0000-0003-0857-7843)
- Weipei Zhu (ORCID: https://orcid.org/0000-0003-0737-9693)
- Ying Chen (ORCID: https://orcid.org/0009-0000-4812-7658)
Institutions
- Soochow University (CN)
- Zhangjiagang First People's Hospital (CN)
- Second Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Biology Direct
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1186/s13062-024-00525-7
- Citations
- 1
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.58