Membrankontaktstellen: wie Organellen miteinander reden

Abstract Membrane contact sites exist between virtually all organelles and in all eukaryotic cells. They allow direct communication between cellular subcompartments via exchange of small molecules and thus integrate the different organellar activities. These contact sites are emerging as hubs for metabolic adaptation. Here, two contact sites that change dramatically in response to starvation serve as examples to illustrate the remodeling of the membrane contact site landscape upon metabolic stress.