Evaluation of a novel biplex rapid diagnostic test for antibody responses to Loa loa and Onchocerca volvulus infections
The sensitivity of each test was good (84-85%) but the diagnostic agreement between the two ARTs was poor, suggesting that IgG and IgG4 antibody responses should be interpreted differently. The assessment of the innovative rapid diagnostic IgG4-SXP-1 biplex test, designed for onchocerciasis and loiasis, shows encouraging sensitivity but underlines the necessity for further in vitro assessment.
Authors
- Jérémy T. Campillo (ORCID: https://orcid.org/0000-0002-4400-5204)
- François Missamou (ORCID: https://orcid.org/0000-0002-6388-0266)
- Marlhand C. Hemilembolo
- Marco A. Biamonte (ORCID: https://orcid.org/0000-0002-6870-6283)
- Cédric B. Chesnais (ORCID: https://orcid.org/0000-0002-8779-977X)
- Sébastien D. S. Pion (ORCID: https://orcid.org/0000-0002-9468-7020)
- Michel Boussinesq
Institutions
- Inserm (FR)
- Université de Montpellier (FR)
- Drugs & Diagnostics for Tropical Diseases (US)
- Institut de Recherche pour le Développement (FR)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1371/journal.pntd.0012567
- Citations
- 4
- Primary Topic
- Parasitic Diseases Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- European Commission
- HORIZON EUROPE European Research Council