Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2–MIR203A–SNAI2 axis
Our study reveals a novel mechanism by which HOXB9 promotes the invasion and metastasis of HCC cells and expands the understanding of the function of HOXB9 in tumor progression and provides a novel therapeutic strategy for curtailing HCC invasion and metastasis.
Authors
- Lingpeng Liu
- Dongnian Du
- Yumin Qiu (ORCID: https://orcid.org/0000-0002-5609-0784)
- Xuzhe Yu
- Dandan Zhang (ORCID: https://orcid.org/0000-0002-8029-6280)
- Zehao Chen (ORCID: https://orcid.org/0000-0003-2432-2234)
- Miao Ye (ORCID: https://orcid.org/0009-0003-9211-352X)
- Wenming Zhang
- Yang Liu (ORCID: https://orcid.org/0009-0003-6585-0145)
- Zijing Li (ORCID: https://orcid.org/0009-0000-4170-2875)
- Jianghua Shao (ORCID: https://orcid.org/0000-0002-1490-4102)
- Jiajuan Li
- Wei Wang (ORCID: https://orcid.org/0000-0003-1568-222X)
Institutions
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12967-024-05690-x
- Citations
- 3
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China