Treatment of Short Stature in Aggrecan-deficient Patients With Recombinant Human GH: 3-year Response
Linear growth improved in a cohort of ACAN-deficient patients treated with rhGH, albeit somewhat attenuated in older participants who entered puberty. Longitudinal follow-up is needed to assess the long-term efficacy of rhGH and adult height outcome.
Authors
- Eirene Alexandrou (ORCID: https://orcid.org/0000-0002-0859-5964)
- Leah Tyzinski
- Vivian Hwa
- Andrew Dauber (ORCID: https://orcid.org/0000-0003-4890-0262)
- Gajanthan Muthuvel (ORCID: https://orcid.org/0000-0001-7101-2357)
- Philippe Backeljauw (ORCID: https://orcid.org/0000-0003-2398-9520)
Institutions
- University of Iowa (US)
- Cincinnati Children's Hospital Medical Center (US)
- Children's National (US)
- George Washington University (US)
- University of Iowa Stead Family Children’s Hospital (US)
- University of Cincinnati (US)
Publication Details
- Journal
- Journal of the Endocrine Society
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1210/jendso/bvae177
- Citations
- 3
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Novo Nordisk