Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR-1707 in healthy adult subjects: two randomized, double-blind, single-ascending-dose, phase 1 studies

Authors

Renpeng Zhou (ORCID: https://orcid.org/0000-0003-2629-0256)
Huiling Qin
Juan Wu (ORCID: https://orcid.org/0000-0002-2580-9936)
Jasmine Williams
Sepehr Shakib (ORCID: https://orcid.org/0000-0002-7199-5733)
Yuru Fan
Quanren Wang
Kai Shen (ORCID: https://orcid.org/0009-0009-0439-635X)
Wei Hu (ORCID: https://orcid.org/0000-0002-4809-7601)
Xuan Zhang (ORCID: https://orcid.org/0000-0001-8775-1699)
Na Li (ORCID: https://orcid.org/0000-0002-9945-4189)
Qin Zhang (ORCID: https://orcid.org/0009-0009-5451-4051)
Jingyue Ma
Yueyue Liu (ORCID: https://orcid.org/0000-0003-3699-6973)
Yue Fei (ORCID: https://orcid.org/0000-0002-4622-6377)
Xu Ye (ORCID: https://orcid.org/0009-0006-5336-3077)
Xiaojing Cui (ORCID: https://orcid.org/0000-0003-0330-7772)
Yaru Yang (ORCID: https://orcid.org/0009-0009-7410-3225)
Sheng Feng (ORCID: https://orcid.org/0000-0003-0883-8345)
Fangli Dong
Zi Ye
Hongyan Qiu (ORCID: https://orcid.org/0000-0002-2978-7850)
Qian Zhang (ORCID: https://orcid.org/0000-0001-5975-9781)

Institutions

University of South Australia (AU)
Anhui Medical University (CN)
Government of South Australia (AU)
Jiangsu Hengrui Medicine (China) (CN)
Second Affiliated Hospital of Anhui Medical University (CN)
Linear Clinical Research (AU)
The University of Adelaide (AU)

Publication Details

Journal: Alzheimer s Research & Therapy
Published: 2024-10-10
DOI: https://doi.org/10.1186/s13195-024-01584-8
Citations: 5
Primary Topic: Drug Transport and Resistance Mechanisms
Type: article
Field-Weighted Citation Impact: 1.41

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article

Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR-1707 in healthy adult subjects: two randomized, double-blind, single-ascending-dose, phase 1 studies

Renpeng Zhou, Huiling Qin, Juan Wu, Jasmine Williams et al.

Oct 10, 2024

5 citations

Alzheimer s Research & Therapy

Drug Transport and Resistance Mechanisms

1.41

article

Safety, tolerability, pharmacokinetics and pharmacodynamics of a single intravenous dose of SHR-1707 in healthy adult subjects: two randomized, double-blind, single-ascending-dose, phase 1 studies

Renpeng Zhou, Huiling Qin, Juan Wu, Jasmine Williams, Sepehr Shakib, Yuru Fan, Quanren Wang, Kai Shen, Wei Hu, Xuan Zhang, Na Li, Qin Zhang, Jingyue Ma, Yueyue Liu, Yue Fei, Xu Ye, Xiaojing Cui, Yaru Yang, Sheng Feng, Fangli Dong, Zi Ye, Hongyan Qiu, Qian Zhang

October 10, 2024article en

5 citations

Abstract

No abstract available for this paper.

Alzheimer s Research & TherapyVol. 16(1)

University of South Australia (AU), Anhui Medical University (CN), Government of South Australia (AU), Jiangsu Hengrui Medicine (China) (CN), Second Affiliated Hospital of Anhui Medical University (CN), Linear Clinical Research (AU), The University of Adelaide (AU)

Good health and well-being

Openalex Percentile: Top 15%

Drug Transport and Resistance Mechanisms

1.41

DOI Open Access PDF OpenAlex

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