Tumor specific in situ synthesis of therapeutic agent for precision cancer therapy
A tumor-specifically degradable Cu-doped polydopamine-based nanosystem is developed to achieve in situ synthesis of antitumor compounds, providing a promising approach to precisely eliminate tumors and heighten chemo-immunotherapy.
Authors
- Miaodeng Liu (ORCID: https://orcid.org/0009-0005-2448-2133)
- Chundong Yao
- Zuoyu Chen
- Lixue Deng
- Zhixin Zhou (ORCID: https://orcid.org/0000-0003-0450-1921)
- Lin Wang (ORCID: https://orcid.org/0000-0001-5716-6587)
- Cheng Zhou (ORCID: https://orcid.org/0000-0001-6502-5442)
- Jia Sun
- Ye Yuan (ORCID: https://orcid.org/0000-0003-0154-5312)
- Jia Liu (ORCID: https://orcid.org/0000-0002-9771-192X)
- Zheng Wang (ORCID: https://orcid.org/0000-0001-9255-2977)
Institutions
- Union Hospital (HK)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12951-024-02825-6
- Citations
- 12
- Primary Topic
- Nanoparticle-Based Drug Delivery
- Type
- article
- Field-Weighted Citation Impact
- 2.08
Funders
- National Natural Science Foundation of China