ELAVL1 regulates glycolysis in nasopharyngeal carcinoma cells through the HMGB3/β-catenin axis
ELAVL1 promotes glycolysis in nasopharyngeal carcinoma cells by interacting with HMGB3 to stabilize HMGB3 mRNA, thereby activating β-catenin pathway. Therefore, targeting the ELAVL1-HMGB3-β-catenin axis has the potential to be a novel approach for treating nasopharyngeal carcinoma.
Authors
- Juan Zhou (ORCID: https://orcid.org/0000-0002-6703-6687)
- Yi Cui (ORCID: https://orcid.org/0000-0002-0936-157X)
- Jinyong Tang
- Minghua Hou
- Jiawen Chen (ORCID: https://orcid.org/0000-0001-7571-2860)
- Haojie Wen
- Qiong Wu (ORCID: https://orcid.org/0009-0006-9223-2467)
- Xiaohan Rong
- Yuanzhao Lan
Institutions
- Chenzhou First People's Hospital (CN)
- Xiangnan University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s10020-024-00941-5
- Citations
- 4
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- Natural Science Foundation of Hunan Province