Prediction of post-ESD esophageal stricture by a nomogram and risk factor analysis of ineffective oral steroids prophylaxis
We established a nomogram for esophageal stricture prediction. Depending on the characteristics of lesions, it is possible to estimate the risk of stricture under routine post-ESD treatments (no steroids or oral steroids). Alternative treatments should be considered if the risk is extremely high, especially for patients with mucosal defects involving 7/8 or more of circumference in which oral steroid treatment tends to be ineffective. The higher glucocorticoid receptor β may indicate potential glucocorticoid resistance.
Authors
- Wei Tian (ORCID: https://orcid.org/0000-0002-2270-7440)
- Panpan Lu (ORCID: https://orcid.org/0000-0002-9751-2947)
- Mei Liu (ORCID: https://orcid.org/0000-0002-7073-6174)
- Ninghui Zhao (ORCID: https://orcid.org/0000-0002-1797-2071)
- Miao-Xin Zhang
- Qiang Ding (ORCID: https://orcid.org/0000-0003-1499-6200)
- Xinxia Feng
- Jin Ma (ORCID: https://orcid.org/0009-0004-9528-7012)
Institutions
- Tongji Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12876-024-03448-9
- Citations
- 7
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China
- Huazhong University of Science and Technology
- Tongji University
- Tongji Medical College, Huazhong University of Science and Technology