Thermal ablation enhances immunotherapeutic effect of IP-001 on orthotopic liver cancer in a rat model
Combination of MWA and IP001 enhances tumor suppression in an orthotopic HCC rat model. The tumor suppression is associated to the enhanced immune responses in terms of recruiting the important cell subpopulations such as CD8 + T-cells and NK cells into tumor microenvironment and abolishing immune suppressor such as Treg cells.
Authors
- Samuel S.K. Lam (ORCID: https://orcid.org/0000-0003-1671-3999)
- Chun Fung Wong (ORCID: https://orcid.org/0000-0001-8375-1173)
- Robert C.G. Martin (ORCID: https://orcid.org/0000-0002-5537-3387)
- Tomas Hode
- Yán Li (ORCID: https://orcid.org/0000-0003-4537-7672)
- David W. Anderson (ORCID: https://orcid.org/0000-0003-3868-0024)
Institutions
- University of Louisville (US)
- NeoPhotonics (United States) (US)
Publication Details
- Journal
- International Journal of Hyperthermia
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1080/02656736.2024.2413591
- Citations
- 1
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.37