Effects of dietary Lactobacillus postbiotics and bacitracin on the modulation of mucosa-associated microbiota and pattern recognition receptors affecting immunocompetence of jejunal mucosa in pigs challenged with enterotoxigenic F18+ Escherichia coli
The F18<sup>+</sup> E. coli challenge compromised intestinal health. Bacitracin increased beneficial bacteria showing a trend towards increasing the intestinal barrier function, possibly by reducing the expression of PRR genes. Lactobacillus postbiotics enhanced the immunocompetence of nursery pigs by increasing the expression of interferon-γ and PGLYRP4, and by reducing TLR4, NOD1, and CD14.
Authors
- Marcos Elias Duarte (ORCID: https://orcid.org/0000-0003-0094-336X)
- Sung Woo Kim (ORCID: https://orcid.org/0000-0003-4591-1943)
- Zixiao Deng (ORCID: https://orcid.org/0009-0008-7731-6149)
Institutions
- North Carolina State University (US)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1186/s40104-024-01098-1
- Citations
- 14
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 4.88
Funders
- U.S. Department of Agriculture
- North Carolina State University
- North Carolina Agricultural Foundation
- National Institute of Food and Agriculture