Hybrid ultra-high and conventional dose rate treatments with electrons and photons for the clinical transfer of FLASH-RT to deep-seated targets: A treatment planning study
From a planning perspective, HUC treatments represent a feasible approach for delivering dosimetrically conformal UHDR treatments, potentially mitigating technical challenges associated with delivering conformal FLASH-RT for deep-seated tumours. While further research is needed to optimize HUC fractionation and delivery schemes for specific patient cohorts, HUC treatments offer a promising avenue for the clinical transfer of FLASH-RT.
Authors
- Michele Zeverino (ORCID: https://orcid.org/0000-0001-9941-8252)
- Raphaël Moeckli (ORCID: https://orcid.org/0000-0002-5885-934X)
- Till T. Böhlen (ORCID: https://orcid.org/0000-0001-7408-0187)
- Fernanda Herrera (ORCID: https://orcid.org/0000-0001-7984-0472)
- François Bochud (ORCID: https://orcid.org/0000-0003-2076-0296)
- Luis Schiappacasse (ORCID: https://orcid.org/0000-0001-7621-1662)
- Jean-François Germond
- Rémy Kinj (ORCID: https://orcid.org/0000-0001-9283-7227)
- Jean Bourhis (ORCID: https://orcid.org/0000-0001-5162-1171)
Institutions
- Institute of Radiation Physics (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Radiotherapy and Oncology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1016/j.radonc.2024.110576
- Citations
- 6
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Swiss Cancer Research Foundation
- Fondation ISREC