Therapeutic effect of bloodletting on bone deterioration induced by hypobaric hypoxia in young rats
This study highlights the detrimental effect of hypobaric hypoxia on the bone microstructure of juvenile rats and underscores the therapeutic potential of bloodletting to ameliorate this condition. Additionally, our study on the regulatory mechanisms mediating the effects of bloodletting on gene expression offers new perspectives on bone alterations. It suggests promising avenues for the development of novel preventative measures and targeted therapies to address the challenges posed by related bone disorders.
Authors
- Yang Zhong (ORCID: https://orcid.org/0000-0002-0517-4582)
- Yunhong Wu (ORCID: https://orcid.org/0000-0001-8074-2781)
- Suying Zhu
- Fengying Zhang (ORCID: https://orcid.org/0000-0002-8161-3268)
- Suyuan Wang (ORCID: https://orcid.org/0000-0002-8977-9027)
- Doudou Hao
- Feng Lin (ORCID: https://orcid.org/0000-0001-9214-6549)
- Yanli Chen (ORCID: https://orcid.org/0000-0002-4198-7687)
- Feng Tang (ORCID: https://orcid.org/0009-0001-4011-7241)
- Zhiyou Shi
- Yongxing Fu
Institutions
- Qinghai University (CN)
- Tibet University (CN)
- Xizang Minzu University (CN)
- Tibet Autonomous Region People's Hospital (CN)
Publication Details
- Journal
- Bone
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1016/j.bone.2024.117281
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00