Impaired brain glucose metabolism in glucagon-like peptide-1 receptor knockout mice
GLP-1R KO mice exhibit impaired brain glucose metabolism to high doses of exogenous glucose, and they also have reduced functional connectivity. This suggests that the GLP-1R KO mouse model may serve as a model for correlated metabolic and functional connectivity loss.
Authors
- Garth J. Thompson (ORCID: https://orcid.org/0000-0002-1125-0799)
- Bowen Shi (ORCID: https://orcid.org/0000-0001-9320-144X)
- Hui Li (ORCID: https://orcid.org/0009-0000-9743-1517)
- Yujiao Fang
- Da Wang (ORCID: https://orcid.org/0009-0004-5880-8608)
Institutions
- ShanghaiTech University (CN)
Publication Details
- Journal
- Nutrition and Diabetes
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1038/s41387-024-00343-w
- Citations
- 9
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China
- Zhejiang University