Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform

Consequently, the present study showed that the novel humanized CLC bsAb JMB2005 may represent a novel therapeutic agent of great clinical potential.

Authors

Publication Details

Journal
Antibody Therapeutics
Published
2024-10-10
DOI
https://doi.org/10.1093/abt/tbae027
Primary Topic
Monoclonal and Polyclonal Antibodies Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform

Xiaodan Cao, Chunyin Gu, Zongda Wang, Haixiang Yu et al.
Antibody Therapeutics
Monoclonal and Polyclonal Antibodies Research
article

Discovery of a common light chain bispecific antibody targeting PD-1 and PD-L1 by Hybridoma-to-Phage-to-Yeast (H2PtY) platform

Xiaodan Cao, Chunyin Gu, Zongda Wang, Haixiang Yu, Huawei Zhang, Peipei Liu, Yukun Yang, Sujun Deng, Fangfang Jia, Xianqing He, Yingying Zhen, Kedong Ouyang
article en

Abstract

Consequently, the present study showed that the novel humanized CLC bsAb JMB2005 may represent a novel therapeutic agent of great clinical potential.

Antibody TherapeuticsVol. 8(1)
Openalex Percentile: Top 71%
Monoclonal and Polyclonal Antibodies Research
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