Astrogliosis Marker [11C]SL25.1188 After COVID-19 With Ongoing Depressive and Cognitive Symptoms
Results strongly support the presence of monoamine oxidase B-labeled astrogliosis in COVID-DC throughout the regions assessed, although the association of greater astrogliosis with fewer symptoms raises the possibility of a protective role. The magnitude of astrogliosis in COVID-DC is greater since the emergence of the Omicron variant.
Authors
- Stephen J. Kish (ORCID: https://orcid.org/0000-0003-0237-1756)
- Natasha Verhoeff
- Joeffre Braga
- Neil Vasdev (ORCID: https://orcid.org/0000-0002-2087-5125)
- Jeffrey H. Meyer (ORCID: https://orcid.org/0000-0003-4684-5052)
- Stefan M. Kloiber (ORCID: https://orcid.org/0000-0002-6838-4114)
- Pablo Rusjan (ORCID: https://orcid.org/0000-0003-0075-2918)
- Isabelle Boileau (ORCID: https://orcid.org/0000-0002-9901-1484)
- Érica Leandro Marciano Vieira (ORCID: https://orcid.org/0000-0002-4147-5614)
- Yuko Koshimori (ORCID: https://orcid.org/0009-0000-0083-0133)
- Muhammad Ishrat Husain (ORCID: https://orcid.org/0000-0001-5771-5750)
- Nathan J. Kolla (ORCID: https://orcid.org/0000-0001-7578-723X)
- Thomas Chao (ORCID: https://orcid.org/0000-0001-7736-3801)
- Mariel Lepra
- Emily J.Y. Kuik
- Wei Wang (ORCID: https://orcid.org/0000-0001-6853-7785)
- Michael Bagby
- Khunsa Faiz
- Zahra Nasser
Institutions
- Centre for Addiction and Mental Health (CA)
- University of British Columbia (CA)
- Douglas Mental Health University Institute (CA)
- Hamilton Health Sciences (CA)
- McMaster University (CA)
Publication Details
- Journal
- Biological Psychiatry
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1016/j.biopsych.2024.09.027
- Citations
- 6
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 2.21
Funders
- Bristol-Myers Squibb
- Sanofi
- Moderna
- University of Toronto
- Canadian Institute for Military and Veteran Health Research
- Department of Psychiatry, University of Toronto
- Canadian Institutes of Health Research
- National Institute of Mental Health