Effect of phosphatase and tensin homolog-induced putative kinase 1/ E3 ubiquitin ligase Parkin mediated mitochondrial autophagy on chronic kidney disease myocardial injury and the intervention mechanism of Shenshuai recipe.
The PINK1/Parkin mitochondrial autophagy pathway in myocardial tissues in 5/6 nephrectomy CKD myocardial injury rats was inhibited. SSR can activate PINK1/Parkin mitochondrial autophagy to enhance mitochondrial autophagy, and play a protective role in myocardial tissues.
Authors
- Guangwei Wei
- Gengxin Liu (ORCID: https://orcid.org/0000-0002-2998-8572)
- Min Guo (ORCID: https://orcid.org/0000-0003-4945-5877)
- Zhang Gedi
- Luo Fuli
- Yan Ziyou
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.20231231.001
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00