Identification and experimental validation of a sialylation–related long noncoding RNA signature for prognosis of bladder cancer
In this study, we examined the relationship between sialylation-related lncRNA and the prognosis of bladder cancer, providing new molecular markers and potential targets for diagnosis and treatment. Our research revealed correlations between sialylation-related lncRNA characteristics and clinicopathological features, potential mechanisms, somatic mutations, immune microenvironment, chemotherapy response, and predicted drug sensitivity in bladder cancer. Additionally, in vitro cellular studies were conducted to validate these findings and lay the groundwork for future clinical applications.
Authors
- Haitao Niu (ORCID: https://orcid.org/0000-0001-6035-3500)
- Xintao Tian (ORCID: https://orcid.org/0000-0002-7843-8681)
- Shengxian Li (ORCID: https://orcid.org/0000-0003-2671-4733)
- Yi Qiao (ORCID: https://orcid.org/0000-0002-4667-9018)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- BMC Urology
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12894-024-01613-6
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Natural Science Foundation of China
- Qingdao University