Extrafollicular CD19lowCXCR5−CD11c− double negative 3 (DN3) B cells are significantly associated with disease activity in females with systemic lupus erythematosus
DN3 B cells are strongly associated with SLE clinical activity pointing to their potential involvement in disease pathogenesis, and CD19 expression level performs accurately as disease activity biomarker.
Authors
- Fanny Noulet
- David Spoerl (ORCID: https://orcid.org/0000-0002-2575-9537)
- Lionel Arlettaz
- Lyssia Gruaz (ORCID: https://orcid.org/0009-0007-1425-0114)
- Loredana Frasca (ORCID: https://orcid.org/0000-0001-6924-3826)
- Alice Horisberger (ORCID: https://orcid.org/0000-0002-3732-8662)
- Camillo Ribi (ORCID: https://orcid.org/0000-0002-0446-9741)
- Carlo Chizzolini (ORCID: https://orcid.org/0000-0003-4849-6335)
- Stéphanie Hugues (ORCID: https://orcid.org/0000-0002-1031-5909)
- Claire Cénac (ORCID: https://orcid.org/0000-0001-6641-7851)
- Jean‐Charles Guéry (ORCID: https://orcid.org/0000-0003-4499-3270)
Institutions
- University of Geneva (CH)
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Istituto Superiore di Sanità (IT)
- Centre Hospitalier Universitaire Vaudois (CH)
- Toulouse Mathematics Institute (FR)
- University Hospital of Geneva (CH)
- Institut des Maladies Métaboliques et Cardiovasculaires (FR)
- Hôpital du Valais (CH)
Publication Details
- Journal
- Journal of Translational Autoimmunity
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1016/j.jtauto.2024.100252
- Citations
- 8
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 1.92
Funders
- Hôpitaux Universitaires de Genève
- Foundation for Research in Rheumatology
- Faculté de Médecine, Université de Genève