HbA1c comparable to fasting glucose in the external validation of the African Diabetes Risk Score and other established risk prediction models in Black South Africans
The models performed comparably, with the ADRS offering a non-invasive way to identify up to 79% of cases. Based on its ease of use and performance, the ADRS is recommended for screening for T2D in certain Black population groups in South Africa. HbA1c as a means of diagnosis also showed comparable performance with FPG. Therefore, further validation studies can potentially use HbA1c as the standard to compare to.
Authors
- André Pascal Kengne (ORCID: https://orcid.org/0000-0002-5183-131X)
- Marlien Pieters (ORCID: https://orcid.org/0000-0003-2849-6370)
- Héléne T. Cronjé (ORCID: https://orcid.org/0000-0001-6855-8324)
- Herculina S. Kruger (ORCID: https://orcid.org/0000-0002-5365-1777)
- Robin C Dolman-Macleod
- Nicola Royce
Institutions
- South African Medical Research Council (ZA)
- University of Copenhagen (DK)
- University of Cape Town (ZA)
- North-West University (ZA)
Publication Details
- Journal
- BMC Endocrine Disorders
- Published
- 2024-10-10
- DOI
- https://doi.org/10.1186/s12902-024-01735-w
- Citations
- 2
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.72
Funders
- Hamilton Health Sciences
- McMaster University
- North-West University