Suppression of the postprandial hyperglycemia in patients with type 2 diabetes by a raw medicinal herb powder is weakened when consumed in ordinary hard gelatin capsules: A randomized crossover clinical trial
This cinnamon's antihyperglycemic action confirms its acarbose-like property to inhibit the activities of the carbohydrate-digesting enzymes α-amylases/α-glucosidases, which is in accordance with its exceptionally high content of raw insoluble fiber. The efficacy of using raw cinnamon as a diabetes treatment strategy seems to require its intake at a specific time before/concomitantly the main hyperglycemic daily meals. Trial registration: Registro Brasileiro de Ensaios Clínicos (ReBEC), number RBR-98tx28b.
Authors
- Daniel C. Moreira (ORCID: https://orcid.org/0000-0003-1961-7281)
- Alexis F. Welker (ORCID: https://orcid.org/0000-0002-5894-005X)
- Caio Eduardo Gonçalves Reis (ORCID: https://orcid.org/0000-0001-7260-9497)
- Andréa Donatti Gallassi (ORCID: https://orcid.org/0000-0003-1852-485X)
- Fernanda Duarte Moreira (ORCID: https://orcid.org/0000-0002-4923-9114)
Institutions
- Universidade de Brasília (BR)
- Secretaria de Estado de Educação do Distrito Federal (BR)
- Ministério da Saúde (BR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1371/journal.pone.0311501
- Citations
- 4
- Primary Topic
- Natural Antidiabetic Agents Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Governo Brasil
- Fundação de Apoio à Pesquisa do Distrito Federal