Genotype distribution and allele frequency of thioester-containing protein 1(Tep1) and its effect on development of Plasmodium oocyst in populations of Anopheles arabiensis in Ethiopia

The alleles identified in populations of An. arabiensis were TEP1*R1 and TEP1*S1. There was no significant variation in TEP1*R1 allele frequency between the high and low transmission areas. Furthermore, An. arabiensis carrying the TEP1*R1 allele was susceptible to Plasmodium infection. Further studies on vector-parasite interactions, particularly on the TEP1 gene, are required for vector control techniques.

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Journal
PLoS ONE
Published
2024-10-09
DOI
https://doi.org/10.1371/journal.pone.0311783
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
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article

Genotype distribution and allele frequency of thioester-containing protein 1(Tep1) and its effect on development of Plasmodium oocyst in populations of Anopheles arabiensis in Ethiopia

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PLoS ONE
Malaria Research and Control
article

Genotype distribution and allele frequency of thioester-containing protein 1(Tep1) and its effect on development of Plasmodium oocyst in populations of Anopheles arabiensis in Ethiopia

Hallelujah Getachew, Ming‐Chieh Lee, James W. Kazura, Xiaoming Wang, Guiyun Yan, Ashenafi Abossie, Kassahun Habtamu, Delenasaw Yewhalaw, Daibin Zhong, Assalif Demissew, Arega Tsegaye, Teshome Degefa
article en

Abstract

The alleles identified in populations of An. arabiensis were TEP1*R1 and TEP1*S1. There was no significant variation in TEP1*R1 allele frequency between the high and low transmission areas. Furthermore, An. arabiensis carrying the TEP1*R1 allele was susceptible to Plasmodium infection. Further studies on vector-parasite interactions, particularly on the TEP1 gene, are required for vector control techniques.

PLoS ONEVol. 19(10)
Jimma University (ET), University of California, Irvine (US), Kotebe University of Education (ET), Ambo University (ET), Center for Global Health (US), Arba Minch University (ET), Addis Ababa University (ET), Case Western Reserve University (US)
Jimma University, National Institutes of Health
Good health and well-being
Openalex Percentile: Top 73%
Malaria Research and Control
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