Low-dose methadone added to another opioid for cancer pain: a multicentre prospective study

For patients experiencing moderate to severe cancer-related pain despite initial opioid treatment, our study found that low-dose methadone, when used in combination with another opioid, was both safe and effective. This supports the use of methadone as an adjunct to opioid-based treatment for cancer pain.

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Publication Details

Journal
Supportive Care in Cancer
Published
2024-10-09
DOI
https://doi.org/10.1007/s00520-024-08835-2
Citations
4
Primary Topic
Pain Management and Opioid Use
Type
article
Field-Weighted Citation Impact
2.57
Controls
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article

Low-dose methadone added to another opioid for cancer pain: a multicentre prospective study

Laurent Calvel, J Pouget, Matthieu Frasca, Stéphane Picard et al.
4 citations
Supportive Care in Cancer
Pain Management and Opioid Use
2.57
article

Low-dose methadone added to another opioid for cancer pain: a multicentre prospective study

Laurent Calvel, J Pouget, Matthieu Frasca, Stéphane Picard, Guillaume Pierre Serge Economos, Luc Chevalier, Erwan Treillet, Romain Chiquet, Olivier Giet, Laure Serresse, Élise Perceau-Chambard, Audrey Lebel, Olivier Renard, Alexis Burnod, Adrien Evin, Paul Antoine Quesnel, Ines Hardouin, Pauline Bessodes, Flora Tremellat-Falière, Marie-Anne Seveque, Maxime Majerus
article en
4 citations

Abstract

For patients experiencing moderate to severe cancer-related pain despite initial opioid treatment, our study found that low-dose methadone, when used in combination with another opioid, was both safe and effective. This supports the use of methadone as an adjunct to opioid-based treatment for cancer pain.

Supportive Care in CancerVol. 32(11)
Inserm (FR), Université Paris Cité (FR), Institut Gustave Roussy (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Lille (FR), Centre Hospitalier Universitaire de Nice (FR), Centre Hospitalier Universitaire de Nantes (FR), Sorbonne Université (FR), Sorbonne Paris Cité (FR), Hopitaux Civils de Colmar (FR), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Centre Léon Bérard (FR), Groupe Hospitalier Diaconesses Croix Saint-Simon (FR), Centre Hospitalier Universitaire de Limoges (FR), Hôpital Lariboisière (FR), Groupe Hospitalier de l'Institut Catholique de Lille (FR), Centre Hospitalier de Dax –Côte d’Argent (FR), Hôpital Saint-Louis (FR), Maison de Sante Protestante de Bordeaux-Bagatelle (FR), Hôpital d'Hautepierre (FR), Infirmerie Protestante (FR), Institut Curie (FR), Nantes Université (FR)
Openalex Percentile: Top 10%
Pain Management and Opioid Use
2.57
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