Caffeine improves systemic lupus erythematosus endothelial dysfunction by promoting endothelial progenitor cells survival
Caffeine intake positively correlated with the percentage of circulating EPCs in SLE patients; moreover, caffeine in vitro treatment was able to improve EPC survival and vitality through the inhibition of apoptosis and the promotion of autophagy via A2AR/SIRT3/AMPK pathway.
Authors
- Cristiano Alessandri (ORCID: https://orcid.org/0000-0003-4149-5321)
- Valeria Orefice (ORCID: https://orcid.org/0000-0002-6478-4831)
- G. Buoncuore
- Fabrizio Conti (ORCID: https://orcid.org/0000-0002-1897-049X)
- Carmelo Pirone (ORCID: https://orcid.org/0000-0002-3131-3523)
- Cristiana Barbati (ORCID: https://orcid.org/0000-0003-4121-5342)
- Fulvia Ceccarelli (ORCID: https://orcid.org/0000-0001-5026-8783)
Institutions
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1093/rheumatology/keae453
- Citations
- 8
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.87