Pyruvate stimulates transamination of leucine into α-ketoisocaproic acid and supports 3-methylbutanal production by <i>Lactococcus lactis</i>
These results demonstrate that Lactococcus uses pyruvate to transaminate leucine into α-ketoisocaproic acid which supports 3-methylbutanal production. Surprisingly, GDH activity did not stimulate leucine transamination and 3-methylbutanal production.
Authors
- J.C.M. Wolkers-Rooijackers (ORCID: https://orcid.org/0000-0001-6052-2271)
- Judith Brinkman
- Eddy J. Smid (ORCID: https://orcid.org/0000-0002-6687-5083)
- M.H. Zwietering
- Iris van Swam
- J.B. Brandsma (ORCID: https://orcid.org/0000-0002-6601-9746)
- Kim van Uitert
Institutions
- Unilever Foods Innovation Centre (NL)
- Wageningen University & Research (NL)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1093/jambio/lxae257
- Citations
- 7
- Primary Topic
- Amino Acid Enzymes and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.06
Funders
- Institut National de la Recherche Agronomique