Zhachong Shisanwei pill drug-containing serum protects H2O2-Induced PC12 cells injury by suppressing apoptosis, oxidative stress via regulating the MAPK signaling pathway
Mongolian medicine ZSP demonstrates protective effects against H<sub>2</sub>O<sub>2</sub>-induced oxidative stress and apoptosis in PC12 cells. The underlying mechanism may involve the inhibition of the MAPK signaling pathway, enhancement of antioxidant enzyme activity, reduction of intracellular peroxidation levels, and suppression of intrinsic apoptosis pathways.
Authors
- Liqun Ma (ORCID: https://orcid.org/0000-0003-0846-3491)
- Mingyang Cai (ORCID: https://orcid.org/0000-0001-8063-1002)
- Zhen Yang (ORCID: https://orcid.org/0000-0002-9895-4771)
- Yifan Sun (ORCID: https://orcid.org/0000-0002-6385-0091)
- Xiaoxuan Li (ORCID: https://orcid.org/0009-0005-5929-8248)
- Xianju Huang (ORCID: https://orcid.org/0000-0001-8130-1961)
- Haiying Tong (ORCID: https://orcid.org/0000-0001-8976-7678)
- Limuge Che
- Wuyunsiri Guleng
- Hurile Bagen
- Wulan Qiqige
- Hanqiong Hu
Institutions
- Minzu University of China (CN)
- Henan University of Traditional Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- First Affiliated Hospital of Henan University of Traditional Chinese Medicine (CN)
- Inner Mongolia International Mongolian Hospital (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-09
- DOI
- https://doi.org/10.3389/fphar.2024.1445597
- Citations
- 3
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.74