Identification of key proteins in early-onset Alzheimer’s disease based on WGCNA
In summary, through a protein co-expression network analysis, we identified EOAD-related biological processes and molecular pathways, and screened and validated two key proteins, ERBB2IP and LSP1. These proteins may play an important role in the progression of EOAD, suggesting they could serve as potential therapeutic targets for the disease.
Authors
- Dazhi Li (ORCID: https://orcid.org/0000-0002-7338-7790)
- Qiqiang Tang
- Yaxin Wang (ORCID: https://orcid.org/0000-0002-3507-3969)
- Jinliang Wang (ORCID: https://orcid.org/0000-0001-6138-953X)
Institutions
- University of Science and Technology of China (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2024-10-09
- DOI
- https://doi.org/10.3389/fnagi.2024.1412222
- Citations
- 3
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.98
Funders
- Emory University
- University of Science and Technology of China