Exploring lipodystrophy gene expression in adipocytes: unveiling insights into the pathogenesis of insulin resistance, type 2 diabetes, and clustering diseases (metabolic syndrome) in Asian Indians
Adipose tissue expression of lipodystrophy genes shows an association with MetS and its intermediate phenotypic traits. Mutations of these genes are known to cause congenital lipodystrophy syndromes, whereas their altered expression in adipose tissue contributes to the pathogenesis of IR, T2D, and MetS.
Authors
- Aditya Saxena (ORCID: https://orcid.org/0000-0002-8829-0529)
- Shalu Gupta (ORCID: https://orcid.org/0000-0003-0494-0465)
- Sandeep Kumar Mathur (ORCID: https://orcid.org/0000-0001-7494-4061)
- Ravinder Kumar Lamoria
- Rajendra Mandia
- Venkatesan Radha
- Viswanathan Mohan
- Ranjit Mohan Anjana
- Pradeep Tiwari (ORCID: https://orcid.org/0000-0003-1742-3483)
- Ramesh Chandra Banshiwal
Institutions
- SMS Medical College (IN)
- Madras Diabetes Research Foundation (IN)
- Birla Institute of Scientific Research (IN)
- GLA University (IN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-10-09
- DOI
- https://doi.org/10.3389/fendo.2024.1468824
- Citations
- 2
- Primary Topic
- Nuclear Structure and Function
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Indian Council of Medical Research
- Research Society for the Study of Diabetes in India