Investigation of a Radio-Iodinated Alpha-Mangostin for Targeting Estrogen Receptor Alpha (ERα) in Breast Cancer: In Silico Design, Synthesis, and Biological Evaluation
These results suggested that AM would be a useful platform for the development of a new radiopharmaceutical targeting ERα. Further studies are, however, required to reduce deiodination of [<sup>125</sup>I]I-AM in vivo.
Authors
- Kento Kannaka (ORCID: https://orcid.org/0000-0002-5919-1820)
- Tomoya Uehara (ORCID: https://orcid.org/0000-0002-1140-9800)
- Hiroyuki Suzuki (ORCID: https://orcid.org/0000-0002-9560-4274)
- Toto Subroto (ORCID: https://orcid.org/0000-0002-1629-407X)
- Wiwit Nurhidayah (ORCID: https://orcid.org/0009-0007-7020-0752)
- Taufik Muhammad Fakih (ORCID: https://orcid.org/0000-0001-7155-4412)
- Muchtaridi Muchtaridi (ORCID: https://orcid.org/0000-0002-6156-8025)
Institutions
- Chiba University (JP)
- Bandung Islamic University (ID)
- National Research and Innovation Agency (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/dddt.s479447
- Citations
- 4
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 2.20
Funders
- Chiba University
- Direktorat Jenderal Pendidikan Tinggi