Comparative Analysis of the Intrinsic Disorder Within the Layers of the Human Cornea
Our findings reveal a sophisticated landscape of protein structures where intrinsic disorder varies across layers, suggesting an adaptation of the corneal proteome to the unique physiological demands of each layer. These structural variations may reflect the intricate requirements for corneal transparency, biomechanical stability, and environmental responsiveness.
Authors
- Michael Antonietti (ORCID: https://orcid.org/0000-0001-5526-1396)
- Mak B. Djulbegovic (ORCID: https://orcid.org/0000-0002-4149-7450)
- Jaime D. Martinez (ORCID: https://orcid.org/0000-0001-8307-7465)
- Carol L. Karp (ORCID: https://orcid.org/0000-0002-6452-7181)
- David J. Taylor Gonzalez (ORCID: https://orcid.org/0009-0001-2089-6153)
- Vladimir N. Uversky (ORCID: https://orcid.org/0000-0002-4037-5857)
- Robby Mattes
- Colin K. Kim
Institutions
- University of Miami (US)
- Thomas Jefferson University (US)
- University of South Florida (US)
- USF Health Byrd Alzheimer's Institute (US)
- Wills Eye Hospital (US)
Publication Details
- Journal
- Cornea
- Published
- 2024-10-09
- DOI
- https://doi.org/10.1097/ico.0000000000003706
- Citations
- 1
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.53