JAK2 Mutation Assessment in Thrombotic Events at Unusual Anatomical Sites: Insights from a High-Altitude Cohort
This study reveals that JAK2 mutations are infrequently found in high-altitude patients with unprovoked DVT, PE, or atypical thrombosis. While JAK2 testing is notably relevant for splanchnic vein thrombosis, its routine use for other thrombotic events, particularly with normal CBC results, remains uncertain. Given the study's limitations, further prospective research with larger cohorts is needed to refine guidelines for JAK2 mutation testing in various thrombotic contexts.
Authors
- Abdullah Mohammed Algarni (ORCID: https://orcid.org/0000-0002-1477-4379)
- Mohammed A. Assiri (ORCID: https://orcid.org/0000-0002-9527-229X)
- Omayma Saad Eldeen Bakheet
- Husain Alkhaldy (ORCID: https://orcid.org/0000-0003-0245-7576)
- Ayel Yahya (ORCID: https://orcid.org/0000-0002-7538-8551)
- Muhammad Saboor
Institutions
- King Abdulaziz Medical City (SA)
- University of Sharjah (AE)
- Asir Central Hospital (SA)
- King Khalid University (SA)
Publication Details
- Journal
- International Journal of General Medicine
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/ijgm.s480705
- Citations
- 1
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44
Funders
- King Khalid University