Safety and efficacy of direct oral anticoagulants in chronic kidney disease: a meta-analysis
In this meta-analysis, DOACs reduced major bleeding compared with VKAs in stage 4, stage 5/renal replacement therapy, and CKD stage unspecified patients. Future analysis should evaluate the impact of specific DOACs and dosage on safety and efficacy in this population.
Authors
- Ali Eshaghpour (ORCID: https://orcid.org/0000-0002-7827-5827)
- Daniel Tham (ORCID: https://orcid.org/0000-0003-3531-6243)
- Roger Kou (ORCID: https://orcid.org/0000-0002-0087-1012)
- Pei Ye Li (ORCID: https://orcid.org/0000-0003-3625-1154)
- Lucy Zhao (ORCID: https://orcid.org/0000-0003-4944-2363)
- Mark Crowther (ORCID: https://orcid.org/0000-0003-4986-4873)
- Allen Li (ORCID: https://orcid.org/0000-0001-6615-7295)
- Wenhui Yu (ORCID: https://orcid.org/0000-0002-0684-5237)
- Jayhan Kherani
Institutions
- University of Ottawa (CA)
- University of Toronto (CA)
- McMaster University (CA)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1016/j.rpth.2024.102584
- Citations
- 4
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.61