Middle-aged dogs with low and high Aβ CSF concentrations show differences in energy and stress related metabolic profiles in CSF
The differences observed in metabolomic profiles could help in identifying potential biomarkers for an increased risk of developing amyloid pathology in the brain and open the door to the evaluation of preventive treatments for amyloid pathology in humans.
Authors
- Herman Borghys
- Brian Keppler (ORCID: https://orcid.org/0000-0003-4097-7775)
- Andrew J. Schwab (ORCID: https://orcid.org/0000-0002-1517-4308)
Institutions
- Janssen (Belgium) (BE)
- Metabolon (United States) (US)
Publication Details
- Journal
- Heliyon
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e39104
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- Janssen Research and Development
- Janssen Pharmaceuticals