Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study

Our study identifies specific vancomycin PK models that demonstrate superior predictions across age-BMI categories in MIPD applications. Our findings underscore the importance of tailored model selection for vancomycin management, especially highlighting the need for improved models in younger adult patients. Further research into the clinical implications of model performance is warranted to enhance patient care outcomes.

Authors

Publication Details

Journal
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
Published
2024-10-01
DOI
https://doi.org/10.1002/phar.4613
Citations
7
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
3.13
Controls
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article

Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study

Tiffany Lee, Jasmine H. Hughes, Maria‐Stephanie A. Hughes, Jonathan D. Faldasz
7 citations
Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
Antibiotics Pharmacokinetics and Efficacy
3.13
article

Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study

Tiffany Lee, Jasmine H. Hughes, Maria‐Stephanie A. Hughes, Jonathan D. Faldasz
article en
7 citations

Abstract

Our study identifies specific vancomycin PK models that demonstrate superior predictions across age-BMI categories in MIPD applications. Our findings underscore the importance of tailored model selection for vancomycin management, especially highlighting the need for improved models in younger adult patients. Further research into the clinical implications of model performance is warranted to enhance patient care outcomes.

Pharmacotherapy The Journal of Human Pharmacology and Drug TherapyVol. 44(10)
Good health and well-being
Openalex Percentile: Top 8%
Antibiotics Pharmacokinetics and Efficacy
3.13
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