Impacts of age and BMI on vancomycin model choice in a Bayesian software: Lessons from a very large multi‐site retrospective study
Our study identifies specific vancomycin PK models that demonstrate superior predictions across age-BMI categories in MIPD applications. Our findings underscore the importance of tailored model selection for vancomycin management, especially highlighting the need for improved models in younger adult patients. Further research into the clinical implications of model performance is warranted to enhance patient care outcomes.
Authors
- Tiffany Lee (ORCID: https://orcid.org/0009-0002-7874-458X)
- Jasmine H. Hughes (ORCID: https://orcid.org/0000-0003-3053-1251)
- Maria‐Stephanie A. Hughes (ORCID: https://orcid.org/0000-0003-1700-7965)
- Jonathan D. Faldasz
Publication Details
- Journal
- Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/phar.4613
- Citations
- 7
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 3.13