Immunocytochemistry assessment of vocal fold regeneration after cell‐based implant in rabbits
Implanted human ASC persist in rabbit vocal folds. Some appear to express CD31, an endothelial marker. Smooth muscle actin, a marker of myofibroblast phenotype, was present in all sections regardless of treatment, and was not identified in hASC. Host cells also infiltrate the structure, producing a hybrid host-graft vocal fold.
Authors
- Jennifer L. Long (ORCID: https://orcid.org/0000-0002-4185-2328)
- L. Nicolás
- Hanna K. Mandl
- Feng Schrader
Institutions
- University of California, Los Angeles (US)
- VA Greater Los Angeles Healthcare System (US)
Publication Details
- Journal
- Laryngoscope Investigative Otolaryngology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/lio2.70007
- Citations
- 1
- Primary Topic
- Voice and Speech Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- National Institutes of Health