Cohort profile: a nationwide study in Dutch <i>CHEK2</i> c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands – Hebon-CHEK2
Further data linkages with the Netherlands Cancer Registry will allow prospective follow-up and breast cancer risk assessment in unaffected women at the time of genetic testing, risk of contralateral breast cancer and survival in patients with breast cancer. Also, linkage with the nationwide network and registry of histopathology and cytopathology in The Netherlands (PALGA) allows us to retrieve tumour samples to study tumourigenesis.
Authors
- Denise J. Stommel-Jenner
- Rosa de Groot (ORCID: https://orcid.org/0000-0003-4070-0848)
- Marinus J. Blok (ORCID: https://orcid.org/0000-0002-7935-5933)
- Maartje A. C. Schreurs (ORCID: https://orcid.org/0000-0002-1826-5344)
- Margreet G.E.M. Ausems (ORCID: https://orcid.org/0000-0003-0305-3477)
- Christi J. van Asperen (ORCID: https://orcid.org/0000-0002-1436-7650)
- Lieke P. V. Berger (ORCID: https://orcid.org/0000-0003-3185-559X)
- Willemina R.R. Geurts-Giele (ORCID: https://orcid.org/0000-0003-4452-2620)
- Klaartje van Engelen (ORCID: https://orcid.org/0000-0003-3109-0734)
- Muriel A. Adank (ORCID: https://orcid.org/0000-0002-2417-203X)
- Antoinette Hollestelle
- Maartje J. Hooning
- Johan J P Gille
- Marijke R. Wevers
- Marjanka K. Schmidt
- Frans B. L. Hogervorst
Institutions
- Radboud University Nijmegen (NL)
- Leiden University Medical Center (NL)
- Maastricht University Medical Centre (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- University Medical Center Utrecht (NL)
- Dialyse Centrum Groningen (NL)
- Oncode Institute (NL)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- BMJ Open
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-086688
- Citations
- 2
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Amsterdam University Medical Centers
- Universiteit Leiden
- Rijksuniversiteit Groningen
- Radboud Universiteit
- Erasmus Medisch Centrum
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- KWF Kankerbestrijding
- Leids Universitair Medisch Centrum
- Radboud Universitair Medisch Centrum