TMT‐Based Quantitative Proteomic Profiling of Human Esophageal Cancer Cells Reveals the Potential Mechanism and Potential Therapeutic Targets Associated With Radioresistance
Our results revealed that several proteins including Protein S100-A6 (S100A6), Protein-glutamine gamma-glutamyltransferase 2 (TGM2), Glycogen phosphorylase, brain form (PYGB) were involved in radio-resistance development. These proteins could potentially serve as biomarkers for ESCC radio-resistance and as therapeutic targets to treat radio-resistant ESCC cells.
Authors
- Sónia Rocha (ORCID: https://orcid.org/0000-0002-2413-4981)
- Chao He (ORCID: https://orcid.org/0000-0002-9023-1595)
- Mu Wang (ORCID: https://orcid.org/0009-0007-3584-6873)
- A Ren Bao Li Gao (ORCID: https://orcid.org/0000-0002-9405-2893)
- Yin Chen (ORCID: https://orcid.org/0000-0002-6962-2233)
- Jianying Sun
- Chuanfeng Wu
- Ya Pan
- Jundong Zhou
- Hengrui Chen
- Qianlin Liu
Institutions
- University of Liverpool (GB)
- Xi’an Jiaotong-Liverpool University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- PROTEOMICS - CLINICAL APPLICATIONS
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1002/prca.202400010
- Citations
- 2
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.47