Anti-Müllerian hormone as a diagnostic marker for testicular degeneration in dogs: insights from cryptorchid models
Our results suggest that higher serum levels and tissue expression of AMH are linked to smaller seminiferous tubules and poorer Johnsen scores, reflecting degenerative changes and Sertoli cell dysfunction in retained testicles. Given the similarities in the mechanisms that increase AMH levels in both cryptorchid and non-cryptorchid testicles affected by testicular degeneration, this study recommends using AMH as a marker for diagnosing testicular degeneration in dogs.
Authors
- Koen Chiers (ORCID: https://orcid.org/0000-0002-7449-1047)
- George Nicolae
- Nicolae Tiberiu Constantin (ORCID: https://orcid.org/0000-0001-5320-1963)
- Ann Van Soom (ORCID: https://orcid.org/0000-0001-5010-6311)
- Florin Petrișor Posastiuc (ORCID: https://orcid.org/0000-0002-2082-4539)
- Andreea Iren Șerban (ORCID: https://orcid.org/0000-0003-1862-3524)
- Guilherme Rizzoto (ORCID: https://orcid.org/0000-0002-9423-9658)
- Mario Codreanu (ORCID: https://orcid.org/0000-0003-2676-1599)
- Alexandru Ilie Diaconescu
Institutions
- University of Bucharest (RO)
- University of Agronomic Sciences and Veterinary Medicine of Bucharest (RO)
- Ghent University (BE)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2024-10-07
- DOI
- https://doi.org/10.3389/fvets.2024.1481248
- Citations
- 4
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 2.17
Funders
- Universiteit Gent