Improving Health Outcomes Through Treatment Sequencing Optimization in Multiple Myeloma: A Simulation Model in Transplant‐Ineligible Patients
Model results demonstrate that choosing the most effective treatment upfront is crucial in delaying disease progression thus yielding better survival outcomes in transplant-ineligible patients. There was a clear survival benefit in using daratumumab-based regimens in first line. This modelling exercise highlights the need to raise awareness around the impact of sequencing strategies to improve patient's outcomes.
Authors
- Catarina Geraldes (ORCID: https://orcid.org/0000-0001-8627-6187)
- Catarina Cavalcanti da Silva (ORCID: https://orcid.org/0009-0005-5079-1677)
- Rui Bergantim (ORCID: https://orcid.org/0000-0002-7811-9509)
- Maria C. Neves (ORCID: https://orcid.org/0000-0001-5726-3467)
Institutions
- Champalimaud Foundation (PT)
- Universidade do Porto (PT)
- Hospitais da Universidade de Coimbra (PT)
- IPO Porto (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Cancer Reports
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/cnr2.70027
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.45