Management of a granulosa-theca cell tumor in a female Rottweiler

A 4-year, multiparous Rottweiler female dog, was presented for breeding management. Dog had clinical signs of proestrus and estrus for > 6 weeks, including cornification of vaginal epithelium and low circulating progesterone concentrations (< 2 ng/ml). Transabdominal ultrasonography of the reproductive tract and measurement of circulating hormones (antimüllerian hormone, Inhibin-B, and progesterone) suggested granulosa-theca cell tumor. Affected ovary was removed via laparoscopy. Histopathology confirmed granulosa-theca cell tumor; dog resumed cyclicity 4 months after surgery, had normal estrus and was successfully mated with a young stud dog. Dog was diagnosed pregnant (30 days after LH surge) via transabdominal ultrasonography; 4 amniotic sacs were detected, and 3 grew to term but were not viable at delivery (via cesarian surgery).